How Tup1 partners up with Cyc8 to form a functional repressor.
Do not open unexpected files with double extensions (like TUP1.m4v.exe ) as they can carry malware.
Watch the simulation of how it interacts with histone tails to maintain a repressed chromatin state.
It doesn't bind directly to DNA, but gets recruited by sequence-specific binding proteins.
I just uploaded to our shared drive. The video covers how the Tup1–Cyc8 complex acts as a master regulator in yeast, specifically focusing on its ability to mask activation domains and recruit histone deacetylases to silence target genes.