The game is a fast-paced hack-and-slash that stays true to PlatinumGames' signature style, though it focuses heavily on team synergy.

: Each turtle has a specific role. For example, using Donatello on enemy terminals is much faster than using the other turtles.

: You can equip and upgrade four special "Ninjutsu" moves per turtle. Standouts include Leonardo's time-slowing ability and Michelangelo's cheerleading, which resets his brothers' cooldowns.

: Always use your tactical scan to tag enemies through walls and plan your approach before jumping into a fight.

: The difficulty spikes significantly on "Hard" and "Very Hard." Replaying stages to earn Battle Points for Ninjutsu upgrades is essential.

: You can perform stealth takedowns on Foot Soldiers in many stages, which is often safer than a direct brawl in higher-difficulty modes.