: Research compounds like EMD638683 , GSK650394 , and SI113 are being studied for their potential to treat cancer, metabolic disorders, and fibrotic diseases. Serum and glucocorticoid-regulated kinase 1 - Frontiers
: It inhibits apoptosis by phosphorylating and inactivating pro-apoptotic factors like FOXO3a and p53 . SGK1 4 zip
: SGK1 often acts as an oncogene , promoting tumor cell proliferation, metastasis, and resistance to therapies (e.g., Akt inhibitors) in breast, colon, and prostate cancers. : Research compounds like EMD638683 , GSK650394 ,