A fluorescent probe (like IRDye®) is injected into the subject.
By tagging medications (such as encapsulated liposomes) with fluorescent markers, scientists can monitor how long a drug stays in the bloodstream and whether it successfully reaches the tumor site. This is critical for improving the efficiency of chemotherapy. 3. Longitudinal Tumor Studies PearlCAM
The workflow for a research team using PearlCAM typically follows three stages: A fluorescent probe (like IRDye®) is injected into
Because the imaging is non-invasive, researchers can scan the same animal over days or weeks. This reduces the number of animals needed for a study and provides a more accurate timeline of how a tumor grows or shrinks in response to treatment. 🛠 Features and Workflow 🛠 Features and Workflow The system is a
The system is a staple in laboratories focusing on translational medicine. Key use cases include: 1. Fluorescence-Guided Surgery
The subject is placed in the imaging chamber. PearlCAM software captures the NIR signal and overlays it on a standard grayscale "white light" image for anatomical context.
Biological tissues naturally glow under certain light; the NIR range used by PearlCAM minimizes this "noise," resulting in much clearer images.