I Put A Spell On You | RECOMMENDED ✰ |

Software for motif discovery and next generation sequencing analysis

HOMER (Hypergeometric Optimization of Motif EnRichment) is a suite of tools for Motif Discovery and ChIP-Seq analysis. It is a collection of command line programs for unix-style operating systems written in mostly perl and c++. Homer was primarily written as a de novo motif discovery algorithm that is well suited for finding 8-12 bp motifs in large scale genomics data.

Hardware Requirements (recommended): 2+ Gb memory (4-8+ Gb), 10+ Gb Hard Drive space (50+ Gb)
Software Requirements: Unix compatible OS (or cygwin), perl, gcc, make, wget (optional for full functionality: R, DESeq2, blat, bedGraphToBigWig, liftOver)
License: GPLv3

HOMER works on pretty much any Linux/UNIX systems, including MacOS (if Xcode compilers are installed) and on Windows using either cygwin or a Linux subsystem.

If you are looking specifically for HOMER2, you are in the right place! HOMER2 is integrated into HOMER.

Full Program Download

I Put A Spell On You | RECOMMENDED ✰ |

Originally written by as a standard blues ballad to lament a breakup, the track took a wild turn during a recording session for OKeh Records. Legend holds that producer Arnold Maxin brought in a feast of ribs, chicken, and ample alcohol, turning the session into a drunken party.

Hawkins famously claimed he didn’t even remember the recording session. When he woke up, he found he had created a version filled with guttural moans, animalistic grunts, and raw screams. This "cannibalistic" style led many radio stations to ban the song, but it nonetheless sold over a million copies and earned him the lifelong moniker "Screamin' Jay Hawkins". A Legacy of Reinvention I Put a Spell on You

What began as a rejected attempt at a refined love song in 1956 has become one of the most enduring and covered tracks in music history. "I Put a Spell on You" is not just a song; it is a cultural phenomenon that pioneered "shock rock," redefined vocal performance, and became an essential part of the cinematic lexicon. The Bizarre Origins of a Classic Originally written by as a standard blues ballad

I Put a Spell on You: From Drunken Ballad to Cinematic Anthem When he woke up, he found he had

Program Components and Older Versions

homer2 program - key executable for HOMER motif discovery (homerCppOnly.*.zip). (This archive actually contains all of the c++ executable, not just homer2). Unzip in the desired directory and simply type "make" to compile the program.

The configuration script really doesn't deal with older versions, but you can download older versions yourself should you really feel like using inferior data or software!

Old Versions of HOMER Software
Old Versions of Organism Packages
Old Versions of Promoter Packages
Old Versions of Genome Packages

Update Information

Change Log - Short description of recent changes

update.txt - Current HOMER configuration list (Currently support human hg17/hg18/hg19, mouse mm8/mm9, rat rn4, X. tropicalis xenTro2, drosophila dm3, and C. elegans ce6, Zebrafish danRer7, yeast sacCer2, Arabidopsis tair10, Rice msu6, Pombe ASM294v1)

Can't figure something out? Questions, comments, concerns, or other feedback:
cbenner@ucsd.edu