: A Bayesian meta-regression tool used by the Global Burden of Disease Study to ensure consistency between disease incidence, prevalence, and mortality data.
: Used to study the causal impact of alcohol, smoking, blood pressure, and cholesterol on various chronic diseases . ⚠️ Challenges to Validity Diseases - Mr Validity
: There are no common causes (confounders) shared between the genetic variants and the outcome. : A Bayesian meta-regression tool used by the
For an MR report to be considered valid, it must demonstrate that the genetic instruments (SNPs) meet these criteria: Diseases - Mr Validity
"Validity" in this context refers to the that a genetic instrument must satisfy to produce reliable, unbiased results. 🔬 Mendelian Randomization (MR) Report