Successful cartilage regeneration relies on three primary cornerstones:
: Utilizing biochemical and biomechanical stimuli to trigger chondrogenic differentiation. 2. Cell Sources and Expansion
: Providing a structural framework that mimics the native extracellular matrix (ECM) and supports cell attachment.
: Selecting cells capable of proliferation and differentiation into mature chondrocytes.
Cartilage Tissue Engineering: Methods and Protocols Cartilage tissue engineering is a rapidly evolving field aimed at regenerating functional hyaline-like tissue to treat defects caused by trauma or degenerative diseases like . Because cartilage is avascular and has limited self-repair capacity, engineered substitutes are essential for restoring joint function. 1. Core Principles & Components
