Atopy 〈Recommended ✮〉

The core of atopy is a Type I hypersensitivity reaction driven by a Type 2 immune response.

Atopy typically follows a predictable chronological progression: The core of atopy is a Type I

: Systemic immune priming eventually leads to upper and lower airway inflammation. 3. Key Management Strategies allergic rhinitis (hay fever)

Atopy is a genetic predisposition toward developing exaggerated IgE-mediated immune responses to common environmental allergens. Clinically, it manifests as a triad of conditions—, allergic rhinitis (hay fever) , and allergic asthma —often appearing sequentially in a pattern known as the "atopic march". 1. Pathophysiology and Mechanism The core of atopy is a Type I