In its primary host, cattle, B. abortus typically localizes in the reproductive tract. The hallmark clinical signs of infection include:
Even with treatment, relapse occurs in 5–15% of cases due to the presence of "persister" cells that remain metabolically active within protective intracellular niches. Current Control and Prevention Strategies
Brucella abortus is a Gram-negative, facultative intracellular bacterium that primarily targets cattle and serves as a major etiological agent of . This zoonotic disease is a critical global concern, causing significant economic losses in the livestock industry and posing a persistent public health threat to humans. While some countries have successfully eradicated the pathogen, it remains endemic in regions including Latin America, the Middle East, Africa, and parts of Asia. Impact on Livestock
Infected animals frequently experience decreased fertility and retained placentas.